Description

Function

1. Skin Depigmentation: Mequinol inhibits the enzyme tyrosinase, which is crucial for melanin production, thereby reducing hyperpigmentation and promoting an even skin tone.
2. Antioxidant Properties: It acts as an antioxidant and can have synergistic effects when combined with other phenolic antioxidants.
3. Potential Estrogenic Activity: Mequinol can promote the production of hERα-dependent chaperones, indicating potential estrogenic activity.
4. Synergistic Effects with Other Agents: When combined with tretinoin, Mequinol enhances its depigmenting effects by inhibiting the protective action of glutathione (GSH) in melanocytes.

Application

• Topical Skin Treatments: Mequinol is commonly used in combination with tretinoin to treat conditions like solar lentigines (age spots), melasma, and other forms of hyperpigmentation.
• Cosmetic Formulations: It is used in skin-lightening creams and lotions to reduce melanin production and improve skin appearance.
• Research: Mequinol is also used in scientific research to study melanogenesis and potential treatments for pigmentation disorders.