Ferrous Bisglycinate Chelate

Ferrous Bisglycinate Chelate

Ferrous Bisglycinate Chelate (FeBC) is a highly stable iron supplement composed of two glycine molecules bound to a ferrous ion (Fe²⁺) through covalent and coordinate covalent bonds. Unlike traditional iron salts (e.g., ferrous sulfate), it has a ring structure that enhances its bioavailability and reduces gastrointestinal side effects. It is a brownish-black or gray-green powder that is highly soluble in water.

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Description

Function

  1. High Bioavailability:
    • Ferrous Bisglycinate Chelate has at least 2-fold higher bioavailability compared to conventional iron salts like ferrous sulfate. This means smaller doses can be used to achieve the same therapeutic effects.
  2. Reduced Gastrointestinal Side Effects:
    • Unlike other iron salts, FeBC does not cause significant gastrointestinal irritation, making it more tolerable for patients.
  3. Effective in Special Populations:
    • Ferrous Bisglycinate Chelate is particularly effective in treating iron deficiency anemia (IDA) in children and pregnant women. Studies have shown that it can significantly increase hemoglobin levels and improve iron stores with fewer side effects.
  4. Avoids Inhibitors:
    • FeBC is not sequestered by iron absorption inhibitors such as phytates, which are commonly found in cereal-based diets. This makes it more effective in populations with diets high in phytates.
  5. Promotes Overall Nutrient Absorption:
    • In addition to improving iron absorption, FeBC can also enhance the absorption of other essential minerals like calcium, zinc, and selenium.

Application

  1. Nutritional Supplements:
    • Ferrous Bisglycinate Chelate is widely used in dietary supplements to prevent and treat iron deficiency anemia.
  2. Food Fortification:
    • It is added to fortified foods such as milk powder, cereals, and other products to enhance their iron content without causing adverse effects.
  3. Pharmaceuticals:
    • Used in medications to treat iron deficiency anemia, especially in vulnerable populations like children and pregnant women.
  4. Animal Nutrition:
    • Ferrous Bisglycinate Chelate is also used in animal feed to improve iron status and overall health.
  5. Clinical Settings:
    • In clinical trials, FeBC has been shown to be effective in treating iron deficiency anemia with fewer side effects compared to traditional iron salts.