NMNH

NMNH, or Reduced Nicotinamide Mononucleotide, is a novel compound that serves as a precursor to NAD+ (Nicotinamide Adenine Dinucleotide), a crucial molecule involved in cellular energy metabolism and aging processes. It is the reduced form of NMN (Nicotinamide Mononucleotide) and has shown potential for more effective NAD+ enhancement compared to NMN. However, NMNH is less stable and more prone to oxidation, making its storage and application more challenging.

Description

Function

  1. Enhanced NAD+ Production:
    • NMNH is more effective than NMN in increasing NAD+ levels in cells and tissues, with studies showing a 5- to 10-fold increase in NAD+ levels compared to NMN. This enhanced NAD+ production supports cellular energy metabolism and DNA repair processes.
  2. Antioxidant and Anti-Aging Effects:
    • By boosting NAD+ levels, NMNH helps reduce oxidative stress and cellular aging. It can slow down the aging process and improve overall cellular health.
  3. Metabolic Regulation:
    • NMNH inhibits glycolysis and the TCA cycle (Tricarboxylic Acid Cycle), which helps regulate cellular metabolism and prevent metabolic imbalances.
  4. Cellular Repair and Immune Support:
    • NMNH enhances mitochondrial function and supports cellular repair mechanisms, contributing to improved immune function and reduced inflammation.
  5. Inhibition of Abnormal Cell Growth:
    • By inhibiting glycolysis and the TCA cycle, NMNH can suppress the growth of abnormal cells, making it a potential candidate for cancer prevention and treatment.

Application

  1. Anti-Aging Supplements:
    • NMNH is being explored as a more potent alternative to NMN in anti-aging supplements, with the potential to provide longer-lasting and more effective benefits.
  2. Medical and Therapeutic Use:
    • Due to its ability to enhance NAD+ levels and support cellular health, NMNH may be used in the treatment of age-related diseases, metabolic disorders, and neurodegenerative conditions.
  3. Nutraceuticals and Functional Foods:
    • NMNH can be incorporated into nutraceuticals and functional foods to support overall health and wellness, particularly in aging populations.
  4. Cosmetics and Skincare:
    • NMNH may be used in topical applications to promote skin health and reduce signs of aging by enhancing cellular repair and reducing oxidative stress.
  5. Research and Development:
    • NMNH is an active area of research, with ongoing studies exploring its potential benefits and mechanisms of action in various biological systems.