D-Mannose

D-Mannose is a monosaccharide and a C-2 epimer of glucose. It is a naturally occurring sugar found in many plants and fruits. It is a white crystalline powder with a low-calorie, sweet taste.

Description

Function

  • Urinary Tract Health: D-Mannose can prevent bacteria from adhering to the urinary tract lining, thereby helping to protect against urinary tract infections.
  • Immune Regulation: It can enhance the transformation of naive T cells into regulatory T cells (Treg cells), playing an important role in immune regulation.
  • Anti-inflammatory and Antitumor Effects: D-Mannose has been shown to inhibit the activation of macrophages and promote the differentiation of Treg cells, which can help reduce inflammation and has potential antitumor activity.
  • Metabolic Interference: It can interfere with glucose metabolism and transport, which may have applications in managing conditions like diabetes.

Application

  • Food Industry: D-Mannose is used as a low-calorie sweetener and flavor enhancer. It can also act as a humectant, anti-caking agent, and nutritional supplement in various food products.
  • Pharmaceuticals: It is used in the formulation of drugs for urinary tract health and as a component in anti-inflammatory and antitumor medications.
  • Nutraceuticals: D-Mannose is added to dietary supplements for its potential health benefits, including immune support and urinary tract protection.
  • Agriculture: It may have applications in the development of bioactive compounds for plant protection and growth.
  • Research: D-Mannose is used in scientific research to study glycosylation processes, immune responses, and the development of new therapeutic agents.