Nicotinamide Riboside Chloride

Nicotinamide Riboside Chloride

Nicotinamide Riboside Chloride (NR-Cl) is a form of vitamin B3 that serves as an oral precursor to nicotinamide adenine dinucleotide (NAD+). It is known for its ability to increase NAD+ levels, which play a crucial role in cellular metabolism and energy production.

ENQUIRY!

Description

Function

  1. NAD+ Precursor: Nicotinamide Riboside Chloride is a precursor to NAD+, a coenzyme involved in various cellular processes, including DNA repair, energy metabolism, and mitochondrial function.
  2. Activation of Sirtuins: It activates SIRT1 and SIRT3, which are enzymes involved in regulating cellular aging, metabolism, and stress resistance.
  3. Metabolic Support: By increasing NAD+ levels, it enhances oxidative metabolism and helps protect against metabolic abnormalities caused by a high-fat diet.
  4. Neuroprotective Effects: Studies have shown that Nicotinamide Riboside Chloride can reduce cognitive deterioration in Alzheimer’s disease mouse models.
  5. Immune Support: It can enhance the function of poly(ADP-ribose) polymerase (PARP), an enzyme involved in the innate immune response against viruses like COVID-19.

Application

  • Dietary Supplements: Nicotinamide Riboside Chloride is used in dietary supplements to support overall health, aging, and cognitive function.
  • Research: It is widely used in research to study the effects of NAD+ on cellular metabolism, aging, and disease models.
  • Pharmaceuticals: It has potential applications in the development of therapeutic agents for metabolic disorders, neurodegenerative diseases, and other conditions related to cellular aging.
  • Cosmetics: Due to its potential anti-aging effects, Nicotinamide Riboside Chloride may also be used in cosmetic formulations to support skin health.