Pyridoxal 5′-phosphate Monohydrate (PLP) is the active form of Vitamin B6 and serves as an essential cofactor for numerous enzymes involved in amino acid, carbohydrate, and fat metabolism.
Enzyme Cofactor: PLP is a crucial cofactor for many enzymes, including aromatic L-amino acid decarboxylase, which is involved in the synthesis of neurotransmitters like dopamine and serotonin.
Amino Acid Metabolism: It plays a key role in transamination and decarboxylation reactions, essential for the metabolism of amino acids.
Neurotransmitter Synthesis: PLP supports the production of neurotransmitters, which is vital for normal brain function and mood regulation.
Antioxidant Effects: It has been shown to inhibit the formation of advanced glycation end products (AGEs) and prevent oxidative stress.
Cognitive Function: Studies indicate that PLP can alleviate cognitive dysfunction and improve memory in animal models.
Application
Nutritional Supplements: Used as a dietary supplement to support overall health, particularly for brain function and metabolic processes.
Pharmaceuticals: Applied in the treatment of conditions related to neurotransmitter deficiencies, such as depression and cognitive disorders.
Research: Widely used in biochemical research to study enzyme mechanisms, metabolic pathways, and disease mechanisms.
Animal Models: Used in studies to investigate its effects on cognitive function and metabolic health.