Pyridoxal 5-phosphate Monohydrate

Pyridoxal 5′-phosphate Monohydrate (PLP) is the active form of Vitamin B6 and serves as an essential cofactor for numerous enzymes involved in amino acid, carbohydrate, and fat metabolism.

Description

Function

  1. Enzyme Cofactor: PLP is a crucial cofactor for many enzymes, including aromatic L-amino acid decarboxylase, which is involved in the synthesis of neurotransmitters like dopamine and serotonin.
  2. Amino Acid Metabolism: It plays a key role in transamination and decarboxylation reactions, essential for the metabolism of amino acids.
  3. Neurotransmitter Synthesis: PLP supports the production of neurotransmitters, which is vital for normal brain function and mood regulation.
  4. Antioxidant Effects: It has been shown to inhibit the formation of advanced glycation end products (AGEs) and prevent oxidative stress.
  5. Cognitive Function: Studies indicate that PLP can alleviate cognitive dysfunction and improve memory in animal models.

Application

  • Nutritional Supplements: Used as a dietary supplement to support overall health, particularly for brain function and metabolic processes.
  • Pharmaceuticals: Applied in the treatment of conditions related to neurotransmitter deficiencies, such as depression and cognitive disorders.
  • Research: Widely used in biochemical research to study enzyme mechanisms, metabolic pathways, and disease mechanisms.
  • Animal Models: Used in studies to investigate its effects on cognitive function and metabolic health.